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Can You Use Disulfiram for Alcohol Withdrawal?

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When a person is suffering from alcoholism, it is not uncommon for certain medications to be prescribed to help the affected individual. This can be the case both during active addiction and throughout the withdrawal process as well. One such medication that has held the attention of the addiction recovery field is disulfiram, which has multiple pharmacological applications. Of these, Banyan’s Milford rehab center is here to ask the question, can you use disulfiram for alcohol withdrawal?

What Is Disulfiram Used For?

The main conditions that disulfiram is used to treat are alcoholism and alcohol dependence. The way the medicine works is that it makes drinking uncomfortable, which deters people from drinking. Alcohol use while taking disulfiram disrupts the body's natural process of breaking down alcohol, which builds up acetaldehyde, a poisonous chemical that can induce symptoms like headache, palpitations, nausea, and vomiting. The goal of this unpleasant response is to produce a potent deterrent that will strengthen the person's resolve to refrain from drinking.

Disulfiram has been investigated in preclinical and clinical trials for its ability to treat specific forms of cancer, in addition to its involvement in alcohol dependence. Disulfiram may have anti-cancer qualities, such as the capacity to stop the spread of cancer cells, according to research. Although the precise processes underlying its possible anti-cancer properties are still being studied, it is believed to entail the modification of several cellular functions. It's crucial to remember that disulfiram treatment for cancer is still in its infancy, and further investigation is required to determine its efficacy and safety in this situation.

Exactly How Does Disulfiram Work for Alcoholism?

By blocking the enzyme aldehyde dehydrogenase, which is essential for the liver's breakdown of alcohol, disulfiram acts as a deterrent in the treatment of alcoholism. Disulfiram prevents the conversion of acetaldehyde, a metabolite of alcohol, into acetic acid when a person takes it with alcohol. As a result, the body quickly becomes overloaded with this deadly toxin as acetaldehyde builds up. Many uncomfortable and unpleasant Disulfiram side effects, such as nausea, vomiting, headaches, sweating, and palpitations, are brought on by high acetaldehyde levels. Because of this unfavorable reaction, alcohol consumption is strongly negatively associated, which deters people from drinking while taking disulfiram and strengthens their will to stay sober.

In the treatment of alcoholism, the psychological aspect of the disulfiram mechanism of action is essential. The drug helps people form a conditioned response to alcohol by causing these unpleasant feelings when alcohol is consumed, leading them to link alcohol consumption with discomfort. The goal of this classical conditioning method is to destroy the ingrained association between alcohol and pleasure by offering a concrete deterrent that can encourage long-term abstinence from alcohol and behavioral improvements. Disulfiram works best when the patient is motivated to abstain from alcohol, though, because the drug cannot solve the myriad psychological and social issues that lead to alcoholism.

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Is Disulfiram Used for Alcohol Withdrawal?

Alcohol withdrawal syndrome (AWS) is rarely primarily treated with disulfiram. Following a period of intense and continuous drinking, people who suddenly stop or reduce their alcohol intake may experience alcohol withdrawal, a potentially dangerous and life-threatening illness. AWS can cause a variety of symptoms, from minor tremors and anxiety to more serious conditions like seizures and delirium tremens. Instead of easing the symptoms of alcohol withdrawal brought on by an abrupt stop, disulfiram works by avoiding alcohol usage.

While disulfiram is not a standard intervention for alcohol withdrawal, it is crucial to consider the following points:

  • Purpose: Disulfiram is primarily prescribed for maintaining abstinence in individuals who have already undergone detoxification and are committed to a sober lifestyle.
  • Timing: It is typically initiated after the acute phase of alcohol withdrawal has been successfully managed with appropriate medical supervision and supportive care.
  • Risk of severe reactions: Combining disulfiram with alcohol during the withdrawal phase can lead to severe adverse reactions, including cardiovascular complications and respiratory distress.

While using disulfiram for alcohol withdrawal does not address the acute symptoms, it can play a valuable role in supporting long-term recovery by providing a deterrent against relapse and reinforcing the commitment to a sober lifestyle after the initial withdrawal phase has been safely managed. It is essential for healthcare professionals to assess each individual's specific needs and circumstances when determining the most appropriate interventions for alcohol withdrawal and subsequent maintenance of sobriety.

Detoxing From Alcohol At Banyan Treatment Centers

At Banyan's alcohol detox in Delaware, we stand at the forefront of compassionate and effective care for those seeking to overcome alcohol dependence. Our all-encompassing approach to detoxification includes a dedication to long-term recovery in addition to placing a high priority on the safe management of alcohol withdrawal symptoms. We support people through the difficult process of detoxification by providing evidence-based therapies, skilled medical supervision, and individualized treatment plans with the aim of establishing a strong basis for long-term sobriety.

Our Delaware rehab center is a safe sanctuary where people can find the understanding, support, and resources they need to start a transforming journey toward a better, alcohol-free future. It's not just a place for detoxification. At Banyan, we understand that detox is just the beginning of the process, and our committed staff is here to support people in developing the skills and resilience within our alcohol treatment program.

Call Banyan’s Delaware Rehabs at 888-280-4763 to learn more about how we can help you or a loved one navigate the challenges of withdrawal and addiction.

Alyssa, Director of Digital Marketing
Alyssa, Director of Digital Marketing
Alyssa is the National Director of Digital Marketing and is responsible for a multitude of integrated campaigns and events in the behavioral health and addictions field. All articles have been written by Alyssa and medically reviewed by our Chief Medical Officer, Dr. Darrin Mangiacarne.